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Expanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx)
Trinucleotide exchange (TriNEx) is a method for generating novel molecular diversity during directed evolution by random substitution of one contiguous trinucleotide sequence for another. Single trinucleotide sequences were deleted at random positions in a target gene using the engineered transposon...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490759/ https://www.ncbi.nlm.nih.gov/pubmed/18559360 http://dx.doi.org/10.1093/nar/gkn358 |