Minigene-like inhibition of protein synthesis mediated by hungry codons near the start codon

Rare AGA or AGG codons close to the initiation codon inhibit protein synthesis by a tRNA-sequestering mechanism as toxic minigenes do. To further understand this mechanism, a parallel analysis of protein synthesis and peptidyl-tRNA accumulation was performed using both a set of lacZ constructs where...

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Detalles Bibliográficos
Autores principales: Jacinto-Loeza, Eva, Vivanco-Domínguez, Serafín, Guarneros, Gabriel, Hernández-Sánchez, Javier
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490762/
https://www.ncbi.nlm.nih.gov/pubmed/18583364
http://dx.doi.org/10.1093/nar/gkn395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490762/
https://www.ncbi.nlm.nih.gov/pubmed/18583364
http://dx.doi.org/10.1093/nar/gkn395

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