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Linking the functions of unrelated proteins using a novel directed evolution domain insertion method
We have successfully developed a new directed evolution method for generating integral protein fusions comprising of one domain inserted within another. Creating two connections between the insert and accepting parent domain can result in the inter-dependence of the separate protein activities, thus...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490766/ https://www.ncbi.nlm.nih.gov/pubmed/18559359 http://dx.doi.org/10.1093/nar/gkn363 |