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Rosiglitazone Inhibits Adrenocortical Cancer Cell Proliferation by Interfering with the IGF-IR Intracellular Signaling

Rosiglitazone (RGZ), a thiazolidinedione ligand of the peroxisome proliferator-activated receptor (PPAR)-γ, has been recently described as possessing antitumoral properties. We investigated RGZ effect on cell proliferation in two cell line models (SW13 and H295R) of human adrenocortical carcinoma (A...

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Detalles Bibliográficos
Autores principales: Cantini, Giulia, Lombardi, Adriana, Piscitelli, Elisabetta, Poli, Giada, Ceni, Elisabetta, Marchiani, Sara, Ercolino, Tonino, Galli, Andrea, Serio, Mario, Mannelli, Massimo, Luconi, Michaela
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491299/
https://www.ncbi.nlm.nih.gov/pubmed/18670617
http://dx.doi.org/10.1155/2008/904041