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A Thirty Million Year-Old Inherited Heteroplasmy

Due to essentially maternal inheritance and a bottleneck effect during early oogenesis, newly arising mitochondrial DNA (mtDNA) mutations segregate rapidly in metazoan female germlines. Consequently, heteroplasmy (i.e. the mixture of mtDNA genotypes within an organism) is generally resolved to homop...

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Detalles Bibliográficos
Autores principales: Doublet, Vincent, Souty-Grosset, Catherine, Bouchon, Didier, Cordaux, Richard, Marcadé, Isabelle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491557/
https://www.ncbi.nlm.nih.gov/pubmed/18698356
http://dx.doi.org/10.1371/journal.pone.0002938