Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria

BACKGROUND: Apical Membrane Antigen 1 (AMA1), a polymorphic merozoite surface protein, is a leading blood-stage malaria vaccine candidate. This is the first reported use in humans of an investigational vaccine, AMA1-C1/Alhydrogel, with the novel adjuvant CPG 7909. METHODS: A phase 1 trial was conduc...

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Detalles Bibliográficos
Autores principales: Mullen, Gregory E. D., Ellis, Ruth D., Miura, Kazutoyo, Malkin, Elissa, Nolan, Caroline, Hay, Mhorag, Fay, Michael P., Saul, Allan, Zhu, Daming, Rausch, Kelly, Moretz, Samuel, Zhou, Hong, Long, Carole A., Miller, Louis H., Treanor, John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491586/
https://www.ncbi.nlm.nih.gov/pubmed/18698359
http://dx.doi.org/10.1371/journal.pone.0002940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491586/
https://www.ncbi.nlm.nih.gov/pubmed/18698359
http://dx.doi.org/10.1371/journal.pone.0002940

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