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E2F and p53 Induce Apoptosis Independently during Drosophila Development but Intersect in the Context of DNA Damage
In mammalian cells, RB/E2F and p53 are intimately connected, and crosstalk between these pathways is critical for the induction of cell cycle arrest or cell death in response to cellular stresses. Here we have investigated the genetic interactions between RBF/E2F and p53 pathways during Drosophila d...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491587/ https://www.ncbi.nlm.nih.gov/pubmed/18688282 http://dx.doi.org/10.1371/journal.pgen.1000153 |