Multiple dosing strategies with acetyl L-carnitine (ALCAR) fail to alter age-related hearing loss in the Fischer 344/NHsd rat

BACKGROUND: The Fischer 344/NHsd rat undergoes age-related, progressive, high-frequency hearing loss beginning at age 12 months. The loss has been linked to defects/death in the outer hair cells related to oxidative stress originating in the mitochondria. Acetyl L-carnitine (ALCAR) is known to enhan...

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Detalles Bibliográficos
Autores principales: Bielefeld, Eric C, Coling, Donald, Chen, Guang-Di, Henderson, Donald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491592/
https://www.ncbi.nlm.nih.gov/pubmed/18620587
http://dx.doi.org/10.1186/1477-5751-7-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491592/
https://www.ncbi.nlm.nih.gov/pubmed/18620587
http://dx.doi.org/10.1186/1477-5751-7-4

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