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Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells
BACKGROUND: Prostate cancer progression to androgen independence is the primary cause of mortality by this tumor type. The IGF-1/IGF-1R axis is well known to contribute to prostate cancer initiation, but its contribution to invasiveness and the downstream signalling mechanisms that are involved are...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491598/ https://www.ncbi.nlm.nih.gov/pubmed/18598360 http://dx.doi.org/10.1186/1475-2867-8-10 |