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Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells

BACKGROUND: Prostate cancer progression to androgen independence is the primary cause of mortality by this tumor type. The IGF-1/IGF-1R axis is well known to contribute to prostate cancer initiation, but its contribution to invasiveness and the downstream signalling mechanisms that are involved are...

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Detalles Bibliográficos
Autores principales: Saikali, Zeina, Setya, Hemani, Singh, Gurmit, Persad, Sujata
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491598/
https://www.ncbi.nlm.nih.gov/pubmed/18598360
http://dx.doi.org/10.1186/1475-2867-8-10