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Role of IGF-1/IGF-1R in regulation of invasion in DU145 prostate cancer cells

BACKGROUND: Prostate cancer progression to androgen independence is the primary cause of mortality by this tumor type. The IGF-1/IGF-1R axis is well known to contribute to prostate cancer initiation, but its contribution to invasiveness and the downstream signalling mechanisms that are involved are...

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Detalles Bibliográficos
Autores principales:	Saikali, Zeina, Setya, Hemani, Singh, Gurmit, Persad, Sujata
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491598/ https://www.ncbi.nlm.nih.gov/pubmed/18598360 http://dx.doi.org/10.1186/1475-2867-8-10

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