Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family

BACKGROUND: In contrast to the three mammalian p53 family members, p53, which is generally involved in DNA damage responses, and p63 and p73 which are primarily needed for developmental regulation, cep-1 encodes for the single C. elegans p53-like gene. cep-1 acts as a transcription activator in a pr...

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Detalles Bibliográficos
Autores principales: Greiss, Sebastian, Schumacher, Björn, Grandien, Kaj, Rothblatt, Jonathan, Gartner, Anton
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491638/
https://www.ncbi.nlm.nih.gov/pubmed/18627611
http://dx.doi.org/10.1186/1471-2164-9-334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491638/
https://www.ncbi.nlm.nih.gov/pubmed/18627611
http://dx.doi.org/10.1186/1471-2164-9-334

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