Crystal Structure of Botulinum Neurotoxin Type A in Complex with the Cell Surface Co-Receptor GT1b—Insight into the Toxin–Neuron Interaction

Botulinum neurotoxins have a very high affinity and specificity for their target cells requiring two different co-receptors located on the neuronal cell surface. Different toxin serotypes have different protein receptors; yet, most share a common ganglioside co-receptor, GT1b. We determined the crys...

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Detalles Bibliográficos
Autores principales: Stenmark, Pål, Dupuy, Jérôme, Imamura, Akihiro, Kiso, Makoto, Stevens, Raymond C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493045/
https://www.ncbi.nlm.nih.gov/pubmed/18704164
http://dx.doi.org/10.1371/journal.ppat.1000129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493045/
https://www.ncbi.nlm.nih.gov/pubmed/18704164
http://dx.doi.org/10.1371/journal.ppat.1000129

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