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Anti-microtubule activity of tubeimoside I and its colchicine binding site of tubulin

BACKGROUND: Tubeimoside I (TBMS1) was isolated from the tubers of Bolbostemma paniculatum (Maxim.) Franquet. TBMS1 shows potent anti-tumor activity. The present study was conducted to investigate the anti-microtubule role of TBMS1 and its binding site of tubulin. METHODS: Cell growth inhibition was...

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Detalles Bibliográficos
Autores principales: Ma, Rundi, Song, Gang, You, Wenbing, Yu, Lijian, Su, Weiming, Liao, Mingneng, Zhang, Yongping, Huang, Laizhen, Zhang, Xiaoyu, Yu, Tingxi
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493533/
https://www.ncbi.nlm.nih.gov/pubmed/18030471
http://dx.doi.org/10.1007/s00280-007-0635-0