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TSCOT (+) Thymic Epithelial Cell-Mediated Sensitive CD4 Tolerance by Direct Presentation

Although much effort has been directed at dissecting the mechanisms of central tolerance, the role of thymic stromal cells remains elusive. In order to further characterize this event, we developed a mouse model restricting LacZ to thymic stromal cotransporter (TSCOT)-expressing thymic stromal cells...

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Detalles Bibliográficos
Autores principales: Ahn, Sejin, Lee, Gwanghee, Yang, Soo Jung, Lee, Deokjae, Lee, Seunghyuk, Shin, Hyo Sun, Kim, Min Cheol, Lee, Kee Nyung, Palmer, Douglas C, Theoret, Marc R, Jenkinson, Eric J, Anderson, Graham, Restifo, Nicholas P, Kim, Moon Gyo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494558/
https://www.ncbi.nlm.nih.gov/pubmed/18684012
http://dx.doi.org/10.1371/journal.pbio.0060191