Cargando…
TSCOT (+) Thymic Epithelial Cell-Mediated Sensitive CD4 Tolerance by Direct Presentation
Although much effort has been directed at dissecting the mechanisms of central tolerance, the role of thymic stromal cells remains elusive. In order to further characterize this event, we developed a mouse model restricting LacZ to thymic stromal cotransporter (TSCOT)-expressing thymic stromal cells...
Autores principales: | Ahn, Sejin, Lee, Gwanghee, Yang, Soo Jung, Lee, Deokjae, Lee, Seunghyuk, Shin, Hyo Sun, Kim, Min Cheol, Lee, Kee Nyung, Palmer, Douglas C, Theoret, Marc R, Jenkinson, Eric J, Anderson, Graham, Restifo, Nicholas P, Kim, Moon Gyo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494558/ https://www.ncbi.nlm.nih.gov/pubmed/18684012 http://dx.doi.org/10.1371/journal.pbio.0060191 |
Ejemplares similares
-
Expression Analyses Revealed Thymic Stromal Co-Transporter/Slc46A2 Is in Stem Cell Populations and Is a Putative Tumor Suppressor
por: Kim, Ki Yeon, et al.
Publicado: (2015) -
Differential Requirement for Mesenchyme in the Proliferation and Maturation of Thymic Epithelial Progenitors
por: Jenkinson, William E., et al.
Publicado: (2003) -
Normal T Cell Selection Occurs in CD205-Deficient Thymic Microenvironments
por: Jenkinson, William E., et al.
Publicado: (2012) -
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors
por: Baik, Song, et al.
Publicado: (2013) -
Serial progression of cortical and medullary thymic epithelial microenvironments
por: Alves, Nuno L, et al.
Publicado: (2014)