Prevention of SIV Rectal Transmission and Priming of T Cell Responses in Macaques after Local Pre-exposure Application of Tenofovir Gel

BACKGROUND: The rectum is particularly vulnerable to HIV transmission having only a single protective layer of columnar epithelium overlying tissue rich in activated lymphoid cells; thus, unprotected anal intercourse in both women and men carries a higher risk of infection than other sexual routes....

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Detalles Bibliográficos
Autores principales: Cranage, Martin, Sharpe, Sally, Herrera, Carolina, Cope, Alethea, Dennis, Mike, Berry, Neil, Ham, Claire, Heeney, Jonathan, Rezk, Naser, Kashuba, Angela, Anton, Peter, McGowan, Ian, Shattock, Robin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494562/
https://www.ncbi.nlm.nih.gov/pubmed/18684007
http://dx.doi.org/10.1371/journal.pmed.0050157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494562/
https://www.ncbi.nlm.nih.gov/pubmed/18684007
http://dx.doi.org/10.1371/journal.pmed.0050157

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