Cannabinoid Type 1 Receptor Blockade Promotes Mitochondrial Biogenesis Through Endothelial Nitric Oxide Synthase Expression in White Adipocytes

OBJECTIVE—Cannabinoid type 1 (CB1) receptor blockade decreases body weight and adiposity in obese subjects; however, the underlying mechanism is not yet fully understood. Nitric oxide (NO) produced by endothelial NO synthase (eNOS) induces mitochondrial biogenesis and function in adipocytes. This st...

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Detalles Bibliográficos
Autores principales: Tedesco, Laura, Valerio, Alessandra, Cervino, Cristina, Cardile, Annalisa, Pagano, Claudio, Vettor, Roberto, Pasquali, Renato, Carruba, Michele O., Marsicano, Giovanni, Lutz, Beat, Pagotto, Uberto, Nisoli, Enzo
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494670/
https://www.ncbi.nlm.nih.gov/pubmed/18477809
http://dx.doi.org/10.2337/db07-1623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494670/
https://www.ncbi.nlm.nih.gov/pubmed/18477809
http://dx.doi.org/10.2337/db07-1623

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