Cargando…

T-Cell Promiscuity in Autoimmune Diabetes

OBJECTIVE—It is well established that the primary mediators of β-cell destruction in type 1 diabetes are T-cells. Nevertheless, the molecular basis for recognition of β-cell–specific epitopes by pathogenic T-cells remains ill defined; we seek to further explore this issue. RESEARCH DESIGN AND METHOD...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Li, Wang, Bo, Frelinger, Jeffrey A., Tisch, Roland
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494676/
https://www.ncbi.nlm.nih.gov/pubmed/18492786
http://dx.doi.org/10.2337/db08-0383