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T-Cell Promiscuity in Autoimmune Diabetes

OBJECTIVE—It is well established that the primary mediators of β-cell destruction in type 1 diabetes are T-cells. Nevertheless, the molecular basis for recognition of β-cell–specific epitopes by pathogenic T-cells remains ill defined; we seek to further explore this issue. RESEARCH DESIGN AND METHOD...

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Detalles Bibliográficos
Autores principales:	Li, Li, Wang, Bo, Frelinger, Jeffrey A., Tisch, Roland
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494676/ https://www.ncbi.nlm.nih.gov/pubmed/18492786 http://dx.doi.org/10.2337/db08-0383

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