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Altered Calcium Homeostasis Does Not Explain the Contractile Deficit of Diabetic Cardiomyopathy

OBJECTIVE—This study examines the extent to which the contractile deficit of diabetic cardiomyopathy is due to altered Ca(2+) homeostasis. RESEARCH DESIGN AND METHODS—Measurements of isometric force and intracellular calcium ([Ca(2+)](i), using fura-2/AM) were made in left ventricular (LV) trabecula...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Cannell, Mark B., Phillips, Anthony R.J., Cooper, Garth J.S., Ward, Marie-Louise
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494698/
https://www.ncbi.nlm.nih.gov/pubmed/18492789
http://dx.doi.org/10.2337/db08-0140