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Extreme Clonality in Lymphoblastoid Cell Lines with Implications for Allele Specific Expression Analyses

Lymphoblastoid cell lines (LCL) are being actively and extensively used to examine the expression of specific genes and genome-wide expression profiles, including allele specific expression assays. However, it has recently been shown that approximately 10% of human genes exhibit random patterns of m...

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Detalles Bibliográficos
Autores principales: Plagnol, Vincent, Uz, Elif, Wallace, Chris, Stevens, Helen, Clayton, David, Ozcelik, Tayfun, Todd, John A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494943/
https://www.ncbi.nlm.nih.gov/pubmed/18698422
http://dx.doi.org/10.1371/journal.pone.0002966