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The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins

BACKGROUND: The human POB1/REPS2 (Partner of RalBP1) protein is highly conserved in mammals where it has been suggested to function as a molecular scaffold recruiting proteins involved in vesicular traffic and linking them to the actin cytoskeleton remodeling machinery. More recently POB1/REPS2 was...

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Detalles Bibliográficos
Autores principales: Tomassi, Laura, Costantini, Anna, Corallino, Salvatore, Santonico, Elena, Carducci, Martina, Cesareni, Gianni, Castagnoli, Luisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494995/
https://www.ncbi.nlm.nih.gov/pubmed/18647389
http://dx.doi.org/10.1186/1471-2091-9-21