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I–II Loop Structural Determinants in the Gating and Surface Expression of Low Voltage-Activated Calcium Channels

The intracellular loops that interlink the four transmembrane domains of Ca(2+)- and Na(+)-channels (Ca(v), Na(v)) have critical roles in numerous forms of channel regulation. In particular, the intracellular loop that joins repeats I and II (I–II loop) in high voltage-activated (HVA) Ca(2+) channel...

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Detalles Bibliográficos
Autores principales: Baumgart, Joel P., Vitko, Iuliia, Bidaud, Isabelle, Kondratskyi, Artem, Lory, Philippe, Perez-Reyes, Edward
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495038/
https://www.ncbi.nlm.nih.gov/pubmed/18714336
http://dx.doi.org/10.1371/journal.pone.0002976