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I–II Loop Structural Determinants in the Gating and Surface Expression of Low Voltage-Activated Calcium Channels
The intracellular loops that interlink the four transmembrane domains of Ca(2+)- and Na(+)-channels (Ca(v), Na(v)) have critical roles in numerous forms of channel regulation. In particular, the intracellular loop that joins repeats I and II (I–II loop) in high voltage-activated (HVA) Ca(2+) channel...
Autores principales: | Baumgart, Joel P., Vitko, Iuliia, Bidaud, Isabelle, Kondratskyi, Artem, Lory, Philippe, Perez-Reyes, Edward |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495038/ https://www.ncbi.nlm.nih.gov/pubmed/18714336 http://dx.doi.org/10.1371/journal.pone.0002976 |
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