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Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer

BACKGROUND: Estrogen is a pivotal regulator of cell proliferation in the normal breast and breast cancer. Endocrine therapies targeting the estrogen receptor are effective in breast cancer, but their success is limited by intrinsic and acquired resistance. METHODOLOGY/PRINCIPAL FINDINGS: With the go...

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Detalles Bibliográficos
Autores principales: Musgrove, Elizabeth A., Sergio, C. Marcelo, Loi, Sherene, Inman, Claire K., Anderson, Luke R., Alles, M. Chehani, Pinese, Mark, Caldon, C. Elizabeth, Schütte, Judith, Gardiner-Garden, Margaret, Ormandy, Christopher J., McArthur, Grant, Butt, Alison J., Sutherland, Robert L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496892/
https://www.ncbi.nlm.nih.gov/pubmed/18714337
http://dx.doi.org/10.1371/journal.pone.0002987