Lamin A/C Is a Risk Biomarker in Colorectal Cancer

BACKGROUND: A-type lamins are type V intermediate filament proteins encoded by the gene LMNA. Mutations in LMNA give rise to diverse degenerative diseases related to premature ageing. A-type lamins also influence the activity of the Retinoblastoma protein (pRb) and oncogenes such a β-catenin. Conseq...

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Detalles Bibliográficos
Autores principales: Willis, Naomi D., Cox, Thomas R., Rahman-Casañs, Syed F., Smits, Kim, Przyborski, Stefan A., van den Brandt, Piet, van Engeland, Manon, Weijenberg, Matty, Wilson, Robert G., de Bruïne, Adriaan, Hutchison, Christopher J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496895/
https://www.ncbi.nlm.nih.gov/pubmed/18714339
http://dx.doi.org/10.1371/journal.pone.0002988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496895/
https://www.ncbi.nlm.nih.gov/pubmed/18714339
http://dx.doi.org/10.1371/journal.pone.0002988

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