Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS

BACKGROUND: The enzymes responsible for the synthesis of poly-ADP-ribose are named poly-ADP-ribose polymerases (PARP). PARP-2 is a nuclear protein, which regulates a variety of cellular functions that are mainly controlled by protein-protein interactions. A previously described non-conventional bipa...

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Detalles Bibliográficos
Autores principales: Haenni, Sandra S, Altmeyer, Matthias, Hassa, Paul O, Valovka, Taras, Fey, Monika, Hottiger, Michael O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496901/
https://www.ncbi.nlm.nih.gov/pubmed/18644123
http://dx.doi.org/10.1186/1471-2121-9-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496901/
https://www.ncbi.nlm.nih.gov/pubmed/18644123
http://dx.doi.org/10.1186/1471-2121-9-39

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