Inhibition of Tumor Growth Using Salmonella Expressing Fas Ligand

Intravenous administration of bacteria leads to their accumulation in tumors and to sporadic tumor regression. We therefore explored the hypothesis that Salmonella typhimurium engineered to express the proapoptotic cytokine Fas ligand (FasL) would exhibit enhanced antitumor activity. Immunocompetent...

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Detalles Bibliográficos
Autores principales: Loeffler, Markus, Le’Negrate, Gaelle, Krajewska, Maryla, Reed, John C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496919/
https://www.ncbi.nlm.nih.gov/pubmed/18664657
http://dx.doi.org/10.1093/jnci/djn205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496919/
https://www.ncbi.nlm.nih.gov/pubmed/18664657
http://dx.doi.org/10.1093/jnci/djn205

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