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Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
The purpose of diversity-oriented synthesis is to drive the discovery of small molecules with previously unknown biological functions. Natural products necessarily populate biologically relevant chemical space, since they bind both their biosynthetic enzymes and their target macromolecules. Natural...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496956/ https://www.ncbi.nlm.nih.gov/pubmed/18663392 http://dx.doi.org/10.1039/b706296f |