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Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex
We have shown that a number of anticonvulsant drugs can reduce glutamate release at synapses in the rat entorhinal cortex (EC) in vitro. We have also shown that presynaptic NMDA receptors (NMDAr) tonically facilitate glutamate release at these synapses. In the present study we determined whether, ph...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publishers
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496957/ https://www.ncbi.nlm.nih.gov/pubmed/17980555 http://dx.doi.org/10.1016/j.eplepsyres.2007.09.005 |