Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex

We have shown that a number of anticonvulsant drugs can reduce glutamate release at synapses in the rat entorhinal cortex (EC) in vitro. We have also shown that presynaptic NMDA receptors (NMDAr) tonically facilitate glutamate release at these synapses. In the present study we determined whether, ph...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Wetterstrand, Caroline, Jones, Roland S.G.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2007
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2496957/
https://www.ncbi.nlm.nih.gov/pubmed/17980555
http://dx.doi.org/10.1016/j.eplepsyres.2007.09.005

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