Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells

Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with the invasion and metastatic potential of a variety of tumor-derived cell types. However, t...

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Detalles Bibliográficos
Autores principales: Hong, Xin, Jiang, Feng, Kalkanis, Steven N, Zhang, Zheng Gang, Zhang, Xuepeng, Zheng, Xuguang, Jiang, Hao, Mikkelsen, Tom, Chopp, Michael
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2499998/
https://www.ncbi.nlm.nih.gov/pubmed/18647407
http://dx.doi.org/10.1186/1756-9966-27-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2499998/
https://www.ncbi.nlm.nih.gov/pubmed/18647407
http://dx.doi.org/10.1186/1756-9966-27-23

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