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Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells
Heparanase is an endoglycosidase that degrades heparan sulfate, the main polysaccharide constituent of the extracellular matrix (ECM) and basement membrane. Expression of the heparanase gene is associated with the invasion and metastatic potential of a variety of tumor-derived cell types. However, t...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2499998/ https://www.ncbi.nlm.nih.gov/pubmed/18647407 http://dx.doi.org/10.1186/1756-9966-27-23 |