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DnaC Inactivation in Escherichia coli K-12 Induces the SOS Response and Expression of Nucleotide Biosynthesis Genes

BACKGROUND: Initiation of chromosome replication in E. coli requires the DnaA and DnaC proteins and conditionally-lethal dnaA and dnaC mutants are often used to synchronize cell populations. METHODOLOGY/PRINCIPAL FINDINGS: DNA microarrays were used to measure mRNA steady-state levels in initiation-d...

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Detalles Bibliográficos
Autores principales: Løbner-Olesen, Anders, Slominska-Wojewodzka, Monika, Hansen, Flemming G., Marinus, Martin G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500167/
https://www.ncbi.nlm.nih.gov/pubmed/18714349
http://dx.doi.org/10.1371/journal.pone.0002984