Structural basis for inhibition of homologous recombination by the RecX protein

The RecA/RAD51 nucleoprotein filament is central to the reaction of homologous recombination (HR). Filament activity must be tightly regulated in vivo as unrestrained HR can cause genomic instability. Our mechanistic understanding of HR is restricted by lack of structural information about the regul...

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Detalles Bibliográficos
Autores principales: Ragone, Stefania, Maman, Joseph D, Furnham, Nicholas, Pellegrini, Luca
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500204/
https://www.ncbi.nlm.nih.gov/pubmed/18650935
http://dx.doi.org/10.1038/emboj.2008.145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500204/
https://www.ncbi.nlm.nih.gov/pubmed/18650935
http://dx.doi.org/10.1038/emboj.2008.145

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