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The RNA acetyltransferase driven by ATP hydrolysis synthesizes N(4)-acetylcytidine of tRNA anticodon

The wobble base of Escherichia coli elongator tRNA(Met) is modified to N(4)-acetylcytidine (ac(4)C), which is thought to ensure the precise recognition of the AUG codon by preventing misreading of near-cognate AUA codon. By employing genome-wide screen of uncharacterized genes in Escherichia coli (‘...

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Detalles Bibliográficos
Autores principales: Ikeuchi, Yoshiho, Kitahara, Kei, Suzuki, Tsutomu
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2500205/
https://www.ncbi.nlm.nih.gov/pubmed/18668122
http://dx.doi.org/10.1038/emboj.2008.154