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Vitreous induces heme oxygenase-1 expression mediated by transforming growth factor-β and reactive oxygen species generation in human retinal pigment epithelial cells

PURPOSE: When human retinal pigment epithelial (RPE) cells come in contact with vitreous, they undergo changes in gene expression that include inflammatory and anti-oxidant responses. The effects of vitreous on expression of heme oxygenase-1 (HO-1), metallothionein (MT) -1a and -2a, and c-fos were i...

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Detalles Bibliográficos
Autores principales: Hartung, Ren, Parapuram, Sunil K., Ganti, Ramapriya, Hunt, D. Margaret, Chalam, Kakarla V., Hunt, Richard C.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503184/
https://www.ncbi.nlm.nih.gov/pubmed/17277740