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Microphthalmia, persistent hyperplastic hyaloid vasculature and lens anomalies following overexpression of VEGF-A(188) from the αA-crystallin promoter

PURPOSE: During growth of the embryonic eye, dose- and site-specific expression of heparin-binding growth factors is critical for the formation of an appropriate vascular supply. Overexpression of vascular endothelial growth factor-A(188) (VEGF-A(188)), a strongly heparin-binding, endothelial-specif...

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Detalles Bibliográficos
Autores principales: Rutland, Catrin S., Mitchell, Christopher A., Nasir, Muneeb, Konerding, Moritz A., Drexler, Hannes C.A.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503360/
https://www.ncbi.nlm.nih.gov/pubmed/17277743