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Comparison of human B cell activation by TLR7 and TLR9 agonists

BACKGROUND: Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in response to TLR7 and TLR9 agonists. The direct effects of TLR7 stimulation on human B cells is less understoo...

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Detalles Bibliográficos
Autores principales: Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, Birmachu, Woubalem
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503978/
https://www.ncbi.nlm.nih.gov/pubmed/18652679
http://dx.doi.org/10.1186/1471-2172-9-39