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My sister's keeper?: genomic research and the identifiability of siblings

BACKGROUND: Genomic sequencing of SNPs is increasingly prevalent, though the amount of familial information these data contain has not been quantified. METHODS: We provide a framework for measuring the risk to siblings of a patient's SNP genotype disclosure, and demonstrate that sibling SNP gen...

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Detalles Bibliográficos
Autores principales: Cassa, Christopher A, Schmidt, Brian, Kohane, Isaac S, Mandl, Kenneth D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503988/
https://www.ncbi.nlm.nih.gov/pubmed/18655711
http://dx.doi.org/10.1186/1755-8794-1-32