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Real-time detection of Fe·EDTA/H(2)O(2)-induced DNA cleavage by linear dichroism

The conditions for the measurement of linear dichroism (LD) can be adjusted so as to solely reflect the length and the flexibility of DNA. The real-time detection of the EDTA·Fe(2+)-induced oxidative cleavage of double-stranded native and synthetic DNAs was performed using LD. The decrease in the ma...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Lee, Gil Jun, Jang, Kyeung Joo, Cho, Tae Sub, Kim, Seog K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504293/
https://www.ncbi.nlm.nih.gov/pubmed/18567909
http://dx.doi.org/10.1093/nar/gkn370