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Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus
Considerable interest has been focused on inducing RNA interference (RNAi) in neurons to study gene function and identify new targets for disease intervention. Although small interfering RNAs (siRNAs) have been used to silence genes in neurons, in vivo delivery of RNAi remains a major challenge limi...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504301/ https://www.ncbi.nlm.nih.gov/pubmed/18583367 http://dx.doi.org/10.1093/nar/gkn371 |