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Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus

Considerable interest has been focused on inducing RNA interference (RNAi) in neurons to study gene function and identify new targets for disease intervention. Although small interfering RNAs (siRNAs) have been used to silence genes in neurons, in vivo delivery of RNAi remains a major challenge limi...

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Detalles Bibliográficos
Autores principales: Anesti, Anna-Maria, Peeters, Pieter J., Royaux, Ines, Coffin, Robert S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504301/
https://www.ncbi.nlm.nih.gov/pubmed/18583367
http://dx.doi.org/10.1093/nar/gkn371