Cargando…
Efficient delivery of RNA Interference to peripheral neurons in vivo using herpes simplex virus
Considerable interest has been focused on inducing RNA interference (RNAi) in neurons to study gene function and identify new targets for disease intervention. Although small interfering RNAs (siRNAs) have been used to silence genes in neurons, in vivo delivery of RNAi remains a major challenge limi...
Autores principales: | Anesti, Anna-Maria, Peeters, Pieter J., Royaux, Ines, Coffin, Robert S. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504301/ https://www.ncbi.nlm.nih.gov/pubmed/18583367 http://dx.doi.org/10.1093/nar/gkn371 |
Ejemplares similares
-
Expression of RNA interference triggers from an oncolytic herpes simplex virus results in specific silencing in tumour cells in vitro and tumours in vivo
por: Anesti, Anna-Maria, et al.
Publicado: (2010) -
Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition
por: Blazquez, Lorea, et al.
Publicado: (2012) -
Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system
por: Singh, Atul K., et al.
Publicado: (2016) -
Solid polymeric microparticles enhance the delivery of siRNA to macrophages in vivo
por: Lee, Sungmun, et al.
Publicado: (2009) -
A non-covalent peptide-based carrier for in vivo delivery of DNA mimics
por: Morris, May C., et al.
Publicado: (2007)