Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine†

Reverse gyrase is a peculiar DNA topoisomerase, specific of thermophilic microorganisms, which induces positive supercoiling into DNA molecules in an ATP-dependent reaction. It is a modular enzyme and comprises an N-terminal helicase-like module fused to a C-terminal topoisomerase IA-like domain. Th...

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Detalles Bibliográficos
Autores principales: Valenti, Anna, Perugino, Giuseppe, D’Amaro, Anna, Cacace, Andrea, Napoli, Alessandra, Rossi, Mosè, Ciaramella, Maria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504306/
https://www.ncbi.nlm.nih.gov/pubmed/18614606
http://dx.doi.org/10.1093/nar/gkn418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504306/
https://www.ncbi.nlm.nih.gov/pubmed/18614606
http://dx.doi.org/10.1093/nar/gkn418

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