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Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

The conserved RNA helicase DDX3 is of major medical importance due to its involvement in numerous cancers, human hepatitis C virus (HCV) and HIV. Although DDX3 has been reported to have a wide variety of cellular functions, its precise role remains obscure. Here, we raised a new antibody to DDX3 and...

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Detalles Bibliográficos
Autores principales: Lee, Chung-Sheng, Dias, Anusha P., Jedrychowski, Mark, Patel, Arvind H., Hsu, Jeanne L., Reed, Robin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504307/
https://www.ncbi.nlm.nih.gov/pubmed/18628297
http://dx.doi.org/10.1093/nar/gkn454