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DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight
Alterations in cytosine-5 DNA methylation are frequently observed in most types of human cancer. Although assays utilizing PCR amplification of bisulfite-converted DNA are widely employed to analyze these DNA methylation alterations, they are generally limited in throughput capacity, detection sensi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504308/ https://www.ncbi.nlm.nih.gov/pubmed/18628296 http://dx.doi.org/10.1093/nar/gkn455 |