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DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight

Alterations in cytosine-5 DNA methylation are frequently observed in most types of human cancer. Although assays utilizing PCR amplification of bisulfite-converted DNA are widely employed to analyze these DNA methylation alterations, they are generally limited in throughput capacity, detection sensi...

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Detalles Bibliográficos
Autores principales: Weisenberger, Daniel J., Trinh, Binh N., Campan, Mihaela, Sharma, Shikhar, Long, Tiffany I., Ananthnarayan, Suchitra, Liang, Gangning, Esteva, Francisco J., Hortobagyi, Gabriel N., McCormick, Frank, Jones, Peter A., Laird, Peter W.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504308/
https://www.ncbi.nlm.nih.gov/pubmed/18628296
http://dx.doi.org/10.1093/nar/gkn455