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Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene

A polyguanine/polycytosine (polyG/polyC) tract in the proximal promoter of the vascular endothelial growth factor (VEGF) gene is essential for transcriptional activation. The guanine-rich (G-rich) and cytosine-rich (C-rich) strands on this tract are shown to form specific secondary structures, chara...

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Detalles Bibliográficos
Autores principales: Guo, Kexiao, Gokhale, Vijay, Hurley, Laurence H., Sun, Daekyu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504309/
https://www.ncbi.nlm.nih.gov/pubmed/18614607
http://dx.doi.org/10.1093/nar/gkn380