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Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene
A polyguanine/polycytosine (polyG/polyC) tract in the proximal promoter of the vascular endothelial growth factor (VEGF) gene is essential for transcriptional activation. The guanine-rich (G-rich) and cytosine-rich (C-rich) strands on this tract are shown to form specific secondary structures, chara...
Autores principales: | Guo, Kexiao, Gokhale, Vijay, Hurley, Laurence H., Sun, Daekyu |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504309/ https://www.ncbi.nlm.nih.gov/pubmed/18614607 http://dx.doi.org/10.1093/nar/gkn380 |
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