The role of transcriptional activator GATA-1 at human β-globin HS2

GATA-1 is an erythroid activator that binds β-globin gene promoters and DNase I hypersensitive sites (HSs) of the β-globin locus control region (LCR). We investigated the direct role of GATA-1 interaction at the LCR HS2 enhancer by mutating its binding sites within minichromosomes in erythroid cells...

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Detalles Bibliográficos
Autores principales: Cho, Youngran, Song, Sang-Hyun, Lee, Jong Joo, Choi, Narae, Kim, Chul Geun, Dean, Ann, Kim, AeRi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504316/
https://www.ncbi.nlm.nih.gov/pubmed/18586828
http://dx.doi.org/10.1093/nar/gkn368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504316/
https://www.ncbi.nlm.nih.gov/pubmed/18586828
http://dx.doi.org/10.1093/nar/gkn368

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