The conserved N-terminal basic residues and zinc-finger motifs of HIV-1 nucleocapsid restrict the viral cDNA synthesis during virus formation and maturation

Reverse transcription of the genomic RNA by reverse transcriptase occurs soon after HIV-1 infection of target cells. The viral nucleocapsid (NC) protein chaperones this process via its nucleic acid annealing activities and its interactions with the reverse transcriptase enzyme. To function, NC needs...

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Detalles Bibliográficos
Autores principales: Didierlaurent, Ludovic, Houzet, Laurent, Morichaud, Zakia, Darlix, Jean-Luc, Mougel, Marylène
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504319/
https://www.ncbi.nlm.nih.gov/pubmed/18641038
http://dx.doi.org/10.1093/nar/gkn474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2504319/
https://www.ncbi.nlm.nih.gov/pubmed/18641038
http://dx.doi.org/10.1093/nar/gkn474

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